MTHFR Gene Mutation

MTHFR GENE MUTATION

While researching I found that this genetic condition exists in a good portion of people who have Ulcerative Colitis. The MTHFR gene mutation, which causes the inability of the body to methylate folic acid, sets off a cascade of the body’s inability to methylate numerous different kinds of nutrients ultimately causing a copper toxicity in the body/colon, setting off Ulcerative Colitis symptoms.

Everything we eat we digest, and ultimately it methylates/breaks down into a usable substances for the body to use for things like cell repair, tissue repair etc.

It is important that people with Ulcerative Colitis take supplements of sublingual folic and B12. Read the article on methylation for a more thorough understanding of what it is. I break it down step by step.

People with Ulcerative Colitis also have a tendency to have high homocysteine levels. High homocysteine levels are in indication of the body’s inability to methylate the folic acid. The MTHFR gene mutation plays a big role in this also. High homocysteine levels have been linked to heart disease in some people.

If you have symptoms of Ulcerative Colitis have your B12 levels and your homocysteine levels checked. Ask you doctor about have you DNA checked for the MTHFR gene mutation. If he says no because he didn’t hear about it or hasn’t read the studies showing it is an indicator of a genetic predisposition for UC, check with your local hospitals. They can recommend a doctor who will write script for the test. It may or may not be covered by your insurance, so check first.